Amatallah H.N. ALRawhani, Suzan A.W. Amin And Shaima?a I. Gawdat,

ABSTRACT


Aim: The Aim Of This Prospective, Randomized, Double-blind, Clinical Trial Was To Evaluate The Effect Of A Preoperative, Single, Oral Dose Of 50 Mg Diclofenac Potassium (DP) On The Anesthetic Success Of Buccal Infiltration (BI) With 4% Articaine With Epinephrine 1:200,000 In Mandibular Molars With Symptomatic Irreversible Pulpitis (SIP). Methods: Seventy, Endodontic Emergency Patients With SIP Randomly Received Either 50 Mg DP (Diclofenac Group, N=35) Or Placebo (Placebo Group, N=35) Tablets One Hour Before The Initiation Of Endodontic Therapy. Each Patient Received A BI With 4% Articaine With Epinephrine 1:200,000. Intraoperative Pain Intensity And Incidence At The Different Pain Categories (No, Mild, Moderate, Severe) Was Assessed Using Heft-Parker Visual Analogue Scale (HP-VAS). Success Of Anesthesia Was Defined As No-or-mild Pain During Endodontic Treatment. Data Were Statistically Analyzed And The Significance Level (�) Was Set At 0.05.

Results: There Was No Significant Difference Between The Two Groups Regarding The Main Baseline Characteristics Including: Age, Gender, Pre-operative Pain And Canal-number Distribution (p>0.05). Results Showed No Significant Difference Between Both Groups Regarding Intraoperative Pain Intensity, Pain Incidence Or Success Of Anesthesia (p >0.05). Conclusion: Preoperative Administration Of A Single, Oral Dose Of 50 Mg DP Did Not Seem To Affect The Intraoperative Pain And Success Of BI In Mandibular Molars With SIP.